Platelet Volume and Plateletcrit in Dogs with Presumed Primary Immune-Mediated Thrombocytopenia
نویسندگان
چکیده
منابع مشابه
Platelet Volume and Plateletcrit in Dogs with Presumed Primary Immune‐Mediated Thrombocytopenia
BACKGROUND Mean platelet volume (MPV) and plateletcrit (PCT) are indices used in evaluating immune-mediated thrombocytopenia (IMT) in humans and in dogs with congenital macrothrombocytopenia. These indices may provide clinically valuable information in acquired thrombocytopenia. HYPOTHESIS/OBJECTIVES Dogs with presumed primary IMT will have increased MPV, and therefore platelet mass (PCT) wil...
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Immune-mediated thrombocytopenia (IMT) is a disorder in which bound IgG on the surface of platelets results in platelet removal and alterations in mean platelet volume. Using flow cytometry, alterations in platelet size, platelet surface-associated IgG (PSAIgG), and numbers of reticulated platelets were determined in 13 dogs with primary IMT and 4 dogs with secondary IMT induced by experimental...
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Primary immune thrombocytopenic purpura (ITP) is an acquired immune-mediated disorder characterized by transient or persistent decreased platelet count (<100 × 109/L) that affects children and adults in the absence of other underlying causes.1,2 The low platelet count results from platelet destruction by antiplatelet autoantibodies associated to causes such as insufficient platelet production, ...
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ژورنال
عنوان ژورنال: Journal of Veterinary Internal Medicine
سال: 2014
ISSN: 0891-6640
DOI: 10.1111/jvim.12405